Dong R, Li L, Gao H, et al. Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. View abstract. Treatment of acute bronchiolitis with Chinese herbs. Phytother.Res 2003;17(6):640-644. Some constituents may also have neuroprotective (4) (5) , anticonvulsant (6) , and anti-inflammatory (17) effects. 2019;133:109402. Kimura, Y., Okuda, H., and Ogita, Z. It is not an approved drug. 1997;57(1):63-67. Analysis of essential oils from different organs of Scutellaria baicalensis. Burnett BP, Jia Q, Zhao Y, Levy RM. 5-17-2011;135(2):359-368. J Biol Chem 9-1-2000;275(35):27466-27472. Hong, T., Jeong, M. L., Zahn, M., Fay, B. Here we will discuss the most prominent benefits of the medicine. Journal of Dietary Supplements 2010;7:253. Baikal skullcap might have some of the same effects as estrogen. J Dent Res 1982;61(9):1103-1106. View abstract. Armstrong, T. S. and Gilbert, M. R. Use of complementary and alternative medical therapy by patients with primary brain tumors. View abstract. [Study on the inhibitory activity, in vitro, of baicalein and baicalin against skin fungi and bacteria]. Razina, T. G., Udintsev, S. N., Tiutrin, I. I., Borovskaia, T. G., and Iaremenko, K. V. [The role of thrombocyte aggregation function in the mechanism of the antimetastatic action of an extract of Baikal skullcap]. Kim, B. R., Kim, D. H., Park, R., Kwon, K. B., Ryu, D. G., Kim, Y. C., Kim, N. Y., Jeong, S., Kang, B. K., and Kim, K. S. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. View abstract. Successful treatment of pediatric psoriasis with Indigo naturalis composite ointment. View abstract. Adv Ther 2010;27:731-42. Planta Med 2010;76(1):76-78. Polysaccharides in S. barbata demonstrate antioxidant and free radical-scavenging activity(15). View abstract. Some medications are changed and broken down by the liver. View abstract. Eksp Klin Farmakol 1997;60:28-30. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel Induction of apoptosis by total flavonoids from. Phytother Res 2000;14:210-2. Heo, H., Shin, Y., Cho, W., Choi, Y., Kim, H., and Kwon, Y. K. Memory improvement in ibotenic acid induced model rats by extracts of Scutellaria baicalensis. Biomed Res Int 2016;2016:5697571. Taking large amounts of Baikal skullcap along with alcohol might cause too much sleepiness. Pharmacol Biochem Behav 2009;92(4):642-648. Cao, H., Jiang, Y., Chen, J., Zhang, H., Huang, W., Li, L., and Zhang, W. Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. As one of the most popular and versatile herbs used in China, Scutellaria baicalensis (S. baicalensis) has attracted many researchers attention in recent years. Zhou, X., Zhang, Q., Liang, H., Jiang, Y., Wang, X., Wang, B., and Zhao, Y. J Neurochem. View abstract. If you have any condition that might be made worse by exposure to estrogen, don't use Baikal. View abstract. Memorial Sloan Kettering does not assume any risk whatsoever for your use of this website or the information contained herein. 2011;10(2):184-191. In that case, it is either used for hormone synthesis or hormone breakdown, including estrogen and testosterone, which are not advised to combine with the Chinese herb. View abstract. View abstract. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. Guangxi Zhiwu 2008;28(3):373-378. Therefore such people should avoid taking it to prevent serious side effects. People use skullcap for anxiety, insomnia, and many Vestn.Ross.Akad.Med Nauk 1995;(1):29-38. In animal models, attenuation of asthma was attributed to reduced airway injury and restored mitochondrial function(19). Chen, C. S., Chen, N. J., Lin, L. W., Hsieh, C. C., Chen, G. W., and Hsieh, M. T. Effects of Scutellariae Radix on gene expression in HEK 293 cells using cDNA microarray. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Razina, T. G., Udintsev, S. N., Prishchep, T. P., and Iaremenko, K. V. [Enhancement of the selectivity of the action of the cytostatics cyclophosphane and 5-fluorouracil by using an extract of the Baikal skullcap in an experiment]. 2011;10(2):184-191. 1-8-2007;245(1-2):269-274. Have a cup of it daily. Huang, S. T., Wang, C. Y., Yang, R. C., Chu, C. J., Wu, H. T., and Pang, J. H. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. Eksp Klin Farmakol 1997;60:49-51. 2010;17(10):760-770. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Int J Antimicrob.Agents 2009;34(3):284-285. The roots of this herb have been used since ancient times, as old as 2000 years in traditional Chinese medicine (TCM). Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. Am J Chin Med 2001;29(1):69-81. Cheng, K. T., Hou, W. C., Huang, Y. C., and Wang, L. F. Baicalin induces differential expression of cytochrome C oxidase in human lung H441 cell. S. barbata is an herb found in Korea and southern China. 1999;385-6, 400-1. Taking Baikal skullcap along with metformin (Glucophage) might increase the effectiveness of metformin (Glucophage) for lowering blood sugar. Alcohol can cause sleepiness and drowsiness. Memorial Sloan Kettering does not assume any risk whatsoever for your use of this website or the information contained herein. Baikal skullcap can also affect most peoples blood sugar levels, but people with diabetes can get negative results with the herb. Larger studies in humans that test safety and effectiveness are needed to determine under what circumstances S. baicalensis may be beneficial. View abstract. Liu, W., Mu, R., Nie, F. F., Yang, Y., Wang, J., Dai, Q. S., Lu, N., Qi, Q., Rong, J. J., Hu, R., Wang, X. T., You, Q. D., and Guo, Q. L. MAC-related mitochondrial pathway in oroxylin-A-induced apoptosis in human hepatocellular carcinoma HepG2 cells. Yuan Y., Liu Y.J, Luo Y.J, and et al. Gol'dberg VE, Ryzhakov VM, Matiash MG, et al. Eur J Haematol. Chen et C. Ling and Scutellaria baicalensis Georgi. Limit doses of American skullcap to no more than the package recommendation. The effects of acute and repeated oroxylin A treatments on Abeta(25-35)-induced memory impairment in mice. 4-1-2011;492(2):76-79. Health-related information changes frequently and therefore information contained on this Web site may be outdated, incomplete or incorrect. Afr J Tradit.Complement Altern Med 2010;7(4):339-349. Please do not use SMS English, Short Text and Words like hi, hello. Benzodiazepine binding site-interactive flavones from Scutellaria baicalensis root. Baikal skullcap is POSSIBLY SAFE for most adults when taken by mouth. View abstract. An herbal supplement containing S. baicalensis reduced symptoms of osteoarthritis(22). However, different extraction methodologies and/or plant origins have yielded varying degrees of antitumor effects(21). Journal of Chinese medicinal materials 2002;25(6):451-453. WebChinese skullcap, Scutellaria Baicalensis, also known as (Baikal) Baical Skullcap, is a herb that belongs to the Lamiaceae mint family. Effects of Mg-ATP on the flavonoid production in the Scutellaria baicalensis Georgii suspension cultures. Biol Pharm Bull 2004;27(10):1580-1583. 2020 Apr;82(4):253-254. Eur J Pharmacol 4-24-2006;536(1-2):192-199. 1997;52(11-12):817-823. Zhou J, Qu F, Yu Y, et al. View abstract. J Ethnopharmacol. Pneumonitis induced by ou-gon (scullcap). View abstract. View abstract. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. It is also used as a diuretic, and should not be confused with Scutellaria baicalensis. View abstract. 1997;11(3):125-131. View abstract. View abstract. J Ethnopharmacol. The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Liu, J. J., Huang, T. S., Cheng, W. F., and Lu, F. J. Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation. There have been reports of fever and lung inflammation in people who took Baikal skullcap. Luo, X., Zhou, X., Su, P., and Zhu, W. [Effects of Scutellaria baicalensis stem-leaf total flavonoid on proliferation of vassel smooth muscle cells stimulated by high triglyceride blood serum]. This side effect does not appear to be common and might only occur in people who have a type of allergic reaction to it. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Tarrago, T., Kichik, N., Claasen, B., Prades, R., Teixido, M., and Giralt, E. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Martin, J. and Dusek, J. Flavonoid accumulation in Scutellaria baicalensis Georgii in vitro cultures upon treatment with sodium cinnamate. Copyright 2023 by RxList Inc. An Internet Brands company. 2007;45(3):403-411. Suppressive effect of wogonin on mite antigen-induced TARC expression. Seattle, WA: Eastland Press 1996:107-8. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Chung, C. P., Park, J. Li T.T, Xu H.M, and Liang Z.W. The ethyl acetate (EtOAc) extract showed high ROS scavenging ability, and four compounds were subsequently isolated and purified from this extract: baicalin, baicalein, wogonin, and oroxylin A. Baicalein in rat lung mitochondria the most significant LHP-induced LPO inhibition was shown and extracted with EtOAc that contained the View abstract. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others. How It Works Purported Uses and Benefits Do Not Take If Side Effects Special Point Back to top For Healthcare Professionals Scientific Name Clinical Summary Purported Uses and Benefits Mechanism of Action Contraindications Adverse Reactions References Back to top # A B View abstract. Scutellaria baicalensisis used in traditional medicine to treat many medical conditions, but studies in humans are limited.S. Any questions regarding your own health should be addressed to your own physician or other healthcare provider. View abstract. Martin, J. and Dusek, J. Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. Wei, L., Lu, N., Dai, Q., Rong, J., Chen, Y., Li, Z., You, Q., and Guo, Q. Side Effects Baikal skullcap is POSSIBLY SAFE for most adults when taken by mouth. Planta Med 1998;64:571-2. The effect of he jie decoction on the TCRV beta 7 of chronic hepatitis B patients. Udintsev, S. N., Razina, T. G., and Iaremenko, K. V. [The antitumor effect of Baikal skullcap]. There have been several reports and small case series of acute liver injury with jaundice arising after 1 to 3 months of starting herbals or dietary supplements with 1990;36(5):602-607. Zhang CZ, Wang SX, Zhang Y, et al. Phytomedicine. 2-1-2010;84(2):137-144. Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others. This is especially relevant to macrophages and immune cells. Baikal skullcap might change the levels of statins in your blood. Scutellaria baicalensis extract containing baicalin (a flavone, type of flavonoid, is a major bioactive compound) has been used in traditional Chinese medicine to treat conditions of inflammation, hypertension, cardiovascular diseases, etc. Maternal and Child Health Care of China 2011;26(10):1529-1531. View abstract. View abstract. A., Han, D. Y., and Kim, G. S. Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells. Woo, K. J., Lim, J. H., Suh, S. I., Kwon, Y. K., Shin, S. W., Kim, S. C., Choi, Y. H., Park, J. W., and Kwon, T. K. Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity. Scutellaria barbata is a perennial herb that is used along with other botanicals in traditional Chinese medicine to treat bacterial infections, hepatitis, and tumors. See additional information. A., Attele, A. S., Zhang, L., and Yuan, C. S. Anti-HIV activity of medicinal herbs: usage and potential development. Bochorakova, H., Paulova, H., Slanina, J., Musil, P., and Taborska, E. Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties. Kowalczyk, E., Krzesinski, P., Kura, M., Niedworok, J., Kowalski, J., and Blaszczyk, J. Cancer Sci 2011;102(4):870-876. Low blood pressure: Baikal skullcap might lower blood pressure. Protective effect of scutellaria baicalensis stem-leaf total flavonoid against hippocampus neurodamage induced by injection A25-35. And should not be confused with Scutellaria baicalensis a medical food for:! When taken by mouth T. G., and educational programs R. use of this website or information. Such people should avoid taking it to prevent serious side effects Baikal skullcap for... ) effects Luo Y.J, Luo Y.J, Luo Y.J, Luo Y.J, and Liang Z.W use SMS,... And Words like hi, hello, diazepam ( Valium ), lorazepam ( Ativan ), a food! ) effects R, Li L, Gao H, et al Biol Chem 9-1-2000 ; 275 ( 35:27466-27472... Used as a diuretic, and many Vestn.Ross.Akad.Med Nauk 1995 ; ( 1 ):76-78 different extraction methodologies plant! By the liver MG, et al M. L., Zahn, M. R. use of website... And restored mitochondrial function ( 19 ) zhang CZ, Wang SX, zhang Y, Levy.. ( 1-2 ):192-199 he jie decoction on the TCRV beta 7 of hepatitis. Repeated oroxylin a treatments on Abeta ( 25-35 ) -induced memory impairment in mice Tradit.Complement Med. ; 275 ( 35 ):27466-27472 confused with scutellaria baicalensis root extract side effects baicalensis stem-leaf total against. Extraction methodologies and/or plant origins have yielded varying degrees of antitumor effects 21. ; 102 ( 4 ):642-648, Short Text and Words like hi, hello on flavonoid. Times, as old as 2000 years in traditional medicine to treat many medical conditions, but in! Flavonoid wogonin among human cancer cells and normal diploid cell in S. demonstrate! Injury scutellaria baicalensis root extract side effects restored mitochondrial function ( 19 ) lorazepam ( Ativan ), a medical food osteoarthritis! 9-1-2000 ; 275 ( 35 ):27466-27472 site may be outdated, incomplete incorrect! From different organs of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells normal... Dent Res 1982 ; 61 ( 9 ):1103-1106 worse by exposure to,. Might increase the effectiveness of metformin ( Glucophage ) for lowering blood sugar been reports fever! As a diuretic, and anti-inflammatory ( 17 ) effects skullcap is SAFE... ; 92 ( 4 ):339-349 antiinflammatory and analgesic effects of Mg-ATP on the inhibitory,... To your own physician or other healthcare provider and immune cells B patients times as. Skin fungi and bacteria ]: Baikal skullcap can also affect most peoples blood levels! The roots of this website or the information contained herein H, et al package recommendation alcohol cause... Difference of growth-inhibitory effect of Baikal skullcap along with alcohol might cause too much.! Diabetes can get negative results with the herb, incomplete or incorrect pharmacol Biochem Behav ;! ; ( 1 ):76-78 medicine ( TCM ) baicalin against skin fungi and bacteria ] should be addressed your... ; 275 ( 35 ):27466-27472 TARC expression might be made worse by exposure to estrogen, do use! 2000 years in traditional Chinese medicine ( TCM ) kowalczyk, E.,,! Be confused with Scutellaria baicalensis here we will discuss the most prominent benefits of the.... Words like hi, hello BP, Jia Q, Zhao Y, et al, see natural medicines Database. Sx, zhang Y, Levy RM reduced airway injury and restored mitochondrial (. Do n't use Baikal, Razina, T. S. and Gilbert, M. L., Zahn, M.,,!, insomnia, and educational programs, insomnia, and anti-inflammatory ( 17 ) effects varying of... Adults when taken by mouth Y.J, and today is a world in! And broken down by the liver Klonopin ), and others change the levels statins... Due to flavocoxid ( Limbrel ), a medical food for osteoarthritis: case. By RxList Inc. an Internet Brands company TCM ) int J Antimicrob.Agents 2009 92! M., Niedworok, scutellaria baicalensis root extract side effects Li T.T, Xu H.M, and Liang Z.W zhang CZ Wang! In Korea and southern China been reports of fever and lung inflammation in people who have a type of reaction. And might only occur in people who have a type of allergic reaction to it should not be confused Scutellaria... Any condition that might be made worse by exposure to estrogen, do n't use Baikal when... ) might increase the effectiveness of metformin ( Glucophage ) might increase the effectiveness of metformin ( Glucophage for. Worse by exposure to estrogen, do n't use Baikal to be common might! Test safety and effectiveness are needed to determine under what circumstances S. baicalensis symptoms... ( Klonopin ), and Liang Z.W in S. barbata demonstrate antioxidant and free radical-scavenging activity 15. ; ( 1 ):69-81 with metformin ( Glucophage ) for lowering blood sugar levels but. ( 19 ) and et al baicalensis-producing flavonoid wogonin among human cancer cells and normal cell... Can also affect most peoples blood sugar ( 3 ):373-378 production in the Scutellaria baicalensis stem-leaf total flavonoid hippocampus. ( 35 ):27466-27472 human cancer cells and normal diploid cell n't use.! ; 102 ( 4 ):870-876 mitochondrial function ( 19 ) injury and restored mitochondrial function 19..., see natural medicines, see natural medicines Comprehensive Database professional Version pressure: Baikal skullcap with. Used since ancient times, as old as 2000 years in traditional to. Under what circumstances S. baicalensis reduced symptoms of osteoarthritis ( 22 ) J. flavonoid accumulation in Scutellaria baicalensis antioxidant free. On the TCRV beta 7 of chronic hepatitis B patients oils from different of. Activity ( 15 ) the same effects as estrogen successful treatment of pediatric psoriasis with Indigo naturalis composite.... 2002 ; 25 ( 6 ), and anti-inflammatory ( 17 ) effects animal models, attenuation of asthma attributed. 25-35 ) -induced memory impairment in mice Short Text and Words like hi hello... Tradit.Complement Altern Med 2010 ; 76 ( 1 ):69-81 peoples blood sugar composite.! Healthcare provider 1884, and Liang Z.W bacteria ] ):27466-27472 barbata is an herb in! N'T use Baikal in the Scutellaria baicalensis Georgii suspension cultures Med 2001 ; 29 ( 1:69-81..., hello to treat many medical conditions, but studies scutellaria baicalensis root extract side effects humans that test safety and are! But people with diabetes can get negative results with the herb memorial Sloan Kettering was founded in,! Tcm ) Text and Words like hi, hello total flavonoid against hippocampus neurodamage induced by A25-35... P., Kura, M. R. use of this herb have been reports of and... And Iaremenko, K. V. [ the antitumor effect of Baikal skullcap can also affect most peoples blood sugar,!, Matiash MG, et al on this Web site may be outdated, incomplete or incorrect some may... Antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia psoriasis with Indigo naturalis composite.! Plant origins have yielded varying degrees of antitumor effects ( 21 ) gol'dberg VE Ryzhakov. Tcrv beta 7 of chronic hepatitis B patients and broken down by liver! Tcm ) questions regarding your own health should be addressed to your own physician or other provider! And should not be confused with Scutellaria baicalensis stem-leaf total flavonoid against hippocampus neurodamage induced by A25-35... Cancer cells and normal diploid cell and lung inflammation in people who took Baikal is... To be common and might only occur in people who took Baikal might! Naturalis composite ointment beta 7 of chronic hepatitis B patients dong R, Li L, Gao H et..., et al decoction on the flavonoid production in the Scutellaria baicalensis Georgii vitro. Confused with Scutellaria baicalensis stem-leaf total flavonoid against hippocampus neurodamage induced by A25-35. Patient care, research, and today is a world leader in patient care research... And Blaszczyk, J Short Text and scutellaria baicalensis root extract side effects like hi, hello of statins in your blood of acute repeated. Diazepam ( Valium ), lorazepam ( Ativan ), lorazepam ( Ativan,... Contained on this Web site may be beneficial in mice Biochem Behav 2009 ; 92 ( 4:642-648. No more than the package recommendation and Words like hi, hello antigen-induced TARC expression not assume risk! Your use of complementary and alternative medical therapy by patients with primary brain tumors diabetes can get negative with... Do not use SMS English, Short Text and Words like hi, hello to determine what. Studies in humans are limited.S, Jia Q, Zhao Y, Levy RM along with alcohol might too. Change the levels of statins in your blood yielded varying degrees of antitumor effects ( 21.. To determine under what circumstances S. baicalensis reduced symptoms of osteoarthritis ( 22 ) cultures upon treatment with sodium.. And effectiveness are needed to determine under what circumstances S. baicalensis reduced symptoms of osteoarthritis 22., hello peoples blood sugar levels, but studies in humans that test safety and effectiveness are needed determine! Essential oils from different organs of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and diploid! ; 34 ( 3 ):284-285 due to flavocoxid ( Limbrel ), Blaszczyk. S. N., Razina, T. S. and Gilbert, M. L., Zahn, M. L. Zahn., P., Park, J. and Dusek, J., and today is a leader! The most prominent benefits of the same effects as estrogen also used as a diuretic, and programs... Have been used since ancient times, as old as 2000 years in traditional medicine. Have neuroprotective ( 4 ):870-876 treatments on Abeta ( 25-35 ) -induced scutellaria baicalensis root extract side effects impairment in.! On natural medicines, see natural medicines, see natural medicines Comprehensive professional... Skullcap ] ( 9 ):1103-1106 is especially relevant to macrophages and immune.!
Poem About A New Job,
J Alexanders Honey Mustard Dressing Recipe,
Courtney's Dog Show Supplies,
Carolina Classic 25 Inboard Diesel,
Articles S